PT-141 (Bremelanotide) is a synthetic melanocortin receptor agonist derived from Melanotan II. It is primarily studied for its effects on sexual arousal and libido enhancement in both male and female research subjects. Unlike traditional PDE5 inhibitors, PT-141 acts directly on the brain’s hypothalamic centers to stimulate sexual desire.
This peptide bypasses the vascular system and instead activates MC4R receptors in the central nervous system, which modulate arousal and sexual response. It is widely studied in the context of sexual dysfunction, particularly hypoactive sexual desire disorder (HSDD) and erectile function.
Key Characteristics
| Feature | Description |
|---|---|
| Compound | PT-141 (Bremelanotide) |
| Form | Lyophilized Peptide |
| Strength | Typically 10mg per vial |
| Primary Use | Libido enhancement and sexual function support |
| Benefit | Stimulates sexual arousal via central melanocortin pathways |
Benefits
- Enhances sexual desire and arousal in both males and females
- Acts on the brain, not the cardiovascular system
- Promising research in HSDD and erectile function studies
- On-demand results in preclinical trials
- May support mood and dopamine-related reward pathways
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